Kunoú M, Akaike T, Hatanaka K
Department of Biomolecular Engineering, Tokyo Institute of Technology, Yokohama, Japan.
J Biomater Sci Polym Ed. 1993;5(3):259-62. doi: 10.1163/156856293x00348.
The effects of sulfated polysaccharides on hepatocyte adhesion on the polystyrene dish and fibronectin-coated dish were investigated. Dextran sulfate and synthetic mannopyranan sulfate slightly inhibited hepatocyte adhesion on fibronectin-coated dish, while heparin showed no effect. On the other hand, hepatocyte adhesion on polystyrene dishes was stimulated in the presence of sulfated polysaccharides in the medium.
研究了硫酸化多糖对肝细胞在聚苯乙烯培养皿和纤连蛋白包被培养皿上黏附的影响。硫酸葡聚糖和合成甘露聚糖硫酸酯对肝细胞在纤连蛋白包被培养皿上的黏附略有抑制作用，而肝素则无此作用。另一方面，培养基中存在硫酸化多糖时可促进肝细胞在聚苯乙烯培养皿上的黏附。
