Read A F
Institute of Cell, Animal and Population Biology, University of Edinburgh, UK.
Trends Microbiol. 1994 Mar;2(3):73-6. doi: 10.1016/0966-842x(94)90537-1.
Why is there variation in the virulence of infectious diseases? Virulence can have substantial effects on the genetic contribution of both host and pathogen to future generations. Understanding it therefore requires explanation not only in terms of cellular and molecular mechanisms, but also in evolutionary terms: what is the nature of the selection acting on genes responsible for virulence?
为什么传染病的毒力会存在差异？毒力会对宿主和病原体对后代的基因贡献产生重大影响。因此，要理解它，不仅需要从细胞和分子机制的角度进行解释，还需要从进化的角度进行解释：作用于负责毒力的基因的选择的本质是什么？
