• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

严重急性呼吸综合征冠状病毒2型的流行病学、动力学及进化：一篇综述

SARS-CoV-2 epidemiology, kinetics, and evolution: A narrative review.

作者信息

Alizon Samuel, Sofonea Mircea T

机构信息

CIRB, CNRS, INSERM, Collège de France, Université PSL, Paris, France.

PCCEI, University Montpellier, INSERM, Montpellier, France.

出版信息

Virulence. 2025 Dec;16(1):2480633. doi: 10.1080/21505594.2025.2480633. Epub 2025 Apr 8.

DOI:10.1080/21505594.2025.2480633
PMID:40197159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11988222/
Abstract

Since winter 2019, SARS-CoV-2 has emerged, spread, and evolved all around the globe. We explore 4 y of evolutionary epidemiology of this virus, ranging from the applied public health challenges to the more conceptual evolutionary biology perspectives. Through this review, we first present the spread and lethality of the infections it causes, starting from its emergence in Wuhan (China) from the initial epidemics all around the world, compare the virus to other betacoronaviruses, focus on its airborne transmission, compare containment strategies ("zero-COVID" . "herd immunity"), explain its phylogeographical tracking, underline the importance of natural selection on the epidemics, mention its within-host population dynamics. Finally, we discuss how the pandemic has transformed (or should transform) the surveillance and prevention of viral respiratory infections and identify perspectives for the research on epidemiology of COVID-19.

摘要

自2019年冬季以来，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）在全球出现、传播并进化。我们探讨了该病毒4年的进化流行病学，涵盖从应用公共卫生挑战到更具概念性的进化生物学观点。通过本综述，我们首先介绍它所引起感染的传播情况和致死率，从其在中国武汉出现到在世界各地引发的最初疫情，将该病毒与其他β冠状病毒进行比较，重点关注其空气传播，比较防控策略（“动态清零”与“群体免疫”），解释其系统地理学追踪情况，强调自然选择对疫情的重要性，提及病毒在宿主体内的群体动态。最后，我们讨论这场大流行如何改变（或应该如何改变）病毒性呼吸道感染的监测和预防，并确定COVID-19流行病学研究的方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/8a305fef68a9/KVIR_A_2480633_F0008_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/89982c8f437a/KVIR_A_2480633_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/59fb5a537da1/KVIR_A_2480633_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/1a18a4e6483d/KVIR_A_2480633_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/ad4f0390ab57/KVIR_A_2480633_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/69871a9dcb6b/KVIR_A_2480633_F0005_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/edbf38a24569/KVIR_A_2480633_F0006_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/c2c827c1a1cc/KVIR_A_2480633_F0007_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/8a305fef68a9/KVIR_A_2480633_F0008_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/89982c8f437a/KVIR_A_2480633_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/59fb5a537da1/KVIR_A_2480633_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/1a18a4e6483d/KVIR_A_2480633_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/ad4f0390ab57/KVIR_A_2480633_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/69871a9dcb6b/KVIR_A_2480633_F0005_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/edbf38a24569/KVIR_A_2480633_F0006_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/c2c827c1a1cc/KVIR_A_2480633_F0007_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f18/11988222/8a305fef68a9/KVIR_A_2480633_F0008_OC.jpg

相似文献

1
SARS-CoV-2 epidemiology, kinetics, and evolution: A narrative review.严重急性呼吸综合征冠状病毒2型的流行病学、动力学及进化：一篇综述
Virulence. 2025 Dec;16(1):2480633. doi: 10.1080/21505594.2025.2480633. Epub 2025 Apr 8.
2
Unintended consequences of measures implemented in the school setting to contain the COVID-19 pandemic: a scoping review.学校为遏制新冠疫情而采取的措施所产生的意外后果：一项范围综述。
Cochrane Database Syst Rev. 2024 Dec 12;12(12):CD015397. doi: 10.1002/14651858.CD015397.pub2.
3
Measures implemented in the school setting to contain the COVID-19 pandemic.学校为控制 COVID-19 疫情而采取的措施。
Cochrane Database Syst Rev. 2022 Jan 17;1(1):CD015029. doi: 10.1002/14651858.CD015029.
4
Non-pharmacological measures implemented in the setting of long-term care facilities to prevent SARS-CoV-2 infections and their consequences: a rapid review.长期护理机构中实施的非药物措施以预防 SARS-CoV-2 感染及其后果：快速综述。
Cochrane Database Syst Rev. 2021 Sep 15;9(9):CD015085. doi: 10.1002/14651858.CD015085.pub2.
5
Hospital wastewater surveillance for SARS-CoV-2 identifies intra-hospital dynamics of viral transmission and evolution.对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的医院废水监测可确定病毒传播和进化的医院内部动态。
Appl Environ Microbiol. 2025 Jul 1:e0050125. doi: 10.1128/aem.00501-25.
6
Physical interventions to interrupt or reduce the spread of respiratory viruses.物理干预措施以阻断或减少呼吸道病毒的传播。
Cochrane Database Syst Rev. 2023 Jan 30;1(1):CD006207. doi: 10.1002/14651858.CD006207.pub6.
7
Characterization of SARS-CoV-2 intrahost genetic evolution in vaccinated and non-vaccinated patients from the Kenyan population.肯尼亚人群中接种疫苗和未接种疫苗患者体内 SARS-CoV-2 宿主内基因进化特征分析
J Virol. 2025 Jun 17;99(6):e0048225. doi: 10.1128/jvi.00482-25. Epub 2025 May 6.
8
Drivers of quasispecies development in SARS-CoV-2 and implications for emergent variants and COVID-19.SARS-CoV-2中准种进化的驱动因素及其对新出现变异株和COVID-19的影响。
Virology. 2025 Sep;610:110584. doi: 10.1016/j.virol.2025.110584. Epub 2025 May 26.
9
Long-term serial passaging of SARS-CoV-2 reveals signatures of convergent evolution.严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的长期连续传代揭示了趋同进化的特征。
J Virol. 2025 Jul 22;99(7):e0036325. doi: 10.1128/jvi.00363-25. Epub 2025 Jun 9.
10
Antibody tests for identification of current and past infection with SARS-CoV-2.抗体检测用于鉴定 SARS-CoV-2 的现症感染和既往感染。
Cochrane Database Syst Rev. 2022 Nov 17;11(11):CD013652. doi: 10.1002/14651858.CD013652.pub2.

本文引用的文献

1
Interpretation of indoor air surveillance for respiratory infections: a prospective longitudinal observational study in a childcare setting.儿童保育机构室内空气监测对呼吸道感染的解读：一项前瞻性纵向观察研究
EBioMedicine. 2025 Feb;112:105512. doi: 10.1016/j.ebiom.2024.105512. Epub 2025 Jan 30.
2
Learning the fitness dynamics of pathogens from phylogenies.从系统发育学中了解病原体的适应度动态。
Nature. 2025 Jan;637(8046):683-690. doi: 10.1038/s41586-024-08309-9. Epub 2025 Jan 1.
3
Patterns and drivers of excess mortality during the COVID-19 pandemic in 13 Western European countries.
13个西欧国家在新冠疫情期间的超额死亡率模式及驱动因素。
BMC Glob Public Health. 2024 Dec 9;2(1):78. doi: 10.1186/s44263-024-00103-z.
4
Effect of XBB.1.5-adapted booster vaccination on the imprinting of SARS-CoV-2 immunity.XBB.1.5 适应性加强疫苗接种对 SARS-CoV-2 免疫印记的影响。
NPJ Vaccines. 2024 Nov 21;9(1):231. doi: 10.1038/s41541-024-01023-7.
5
COVID-19 pandemic interventions reshaped the global dispersal of seasonal influenza viruses.COVID-19 大流行干预措施改变了季节性流感病毒的全球传播。
Science. 2024 Nov 8;386(6722):eadq3003. doi: 10.1126/science.adq3003.
6
Fitness models provide accurate short-term forecasts of SARS-CoV-2 variant frequency.健身模特能准确预测 SARS-CoV-2 变异株的流行频率。
PLoS Comput Biol. 2024 Sep 6;20(9):e1012443. doi: 10.1371/journal.pcbi.1012443. eCollection 2024 Sep.
7
Inference of epidemic dynamics in the COVID-19 era and beyond.在新冠疫情时代及之后的传染病动力学推断
Epidemics. 2024 Sep;48:100784. doi: 10.1016/j.epidem.2024.100784. Epub 2024 Jul 31.
8
Estimated number of lives directly saved by COVID-19 vaccination programmes in the WHO European Region from December, 2020, to March, 2023: a retrospective surveillance study.2020 年 12 月至 2023 年 3 月期间，世界卫生组织欧洲区域内由 COVID-19 疫苗接种项目直接挽救的生命估计数：一项回顾性监测研究。
Lancet Respir Med. 2024 Sep;12(9):714-727. doi: 10.1016/S2213-2600(24)00179-6. Epub 2024 Aug 7.
9
Long COVID: a clinical update.长新冠：临床更新。
Lancet. 2024 Aug 17;404(10453):707-724. doi: 10.1016/S0140-6736(24)01136-X. Epub 2024 Jul 31.
10
Long Covid Defined.长新冠的定义。
N Engl J Med. 2024 Nov 7;391(18):1746-1753. doi: 10.1056/NEJMsb2408466. Epub 2024 Jul 31.