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静脉性和非静脉性腿部溃疡:一项人群研究中的临床病史与表现

Venous and non-venous leg ulcers: clinical history and appearance in a population study.

作者信息

Nelzén O, Bergqvist D, Lindhagen A

机构信息

Department of Surgery, Kärnsjukhuset, Skövde, Sweden.

出版信息

Br J Surg. 1994 Feb;81(2):182-7. doi: 10.1002/bjs.1800810206.

Abstract

In a defined Swedish population of 270,800, all patients with current chronic leg ulcers (827) were identified and a random sample of 382 studied in detail. Ulcers of primarily venous cause comprised 54 per cent of the total, giving a point prevalence of 0.16 per cent (95 per cent confidence interval 0.15-0.18 per cent). Half of all patients experienced their first ulcer episode before the age of 65 years, a greater proportion (61 per cent, P < 0.0001) in the subgroup with venous ulcers. The median duration of ulcer diathesis was significantly longer in patients with venous than in those with non-venous lesions (13.4 versus 2.5 years, P < 0.001). About half the patients with venous and non-venous ulcers had had their current lesion for longer than 1 year. Venous ulcers were more often recurrent than those of non-venous type (72 versus 45 per cent of patients, P < 0.0001). Patients with venous ulcers had a significantly higher body mass index (P < 0.001). The number of dressing changes performed per week was 1100 per 100,000 population. The predictive value of 'classical' clinical indicators of venous ulcer did not exceed 0.76. To increase the accuracy of diagnosis of venous ulcer, clinical examination should be combined with non-invasive 'objective' haemodynamic assessment of the venous circulation.

摘要

在瑞典一个特定的270800人的人群中,识别出所有患有慢性腿部溃疡的患者(827例),并对382例进行了详细的随机抽样研究。主要由静脉原因导致的溃疡占总数的54%,点患病率为0.16%(95%置信区间为0.15 - 0.18%)。所有患者中有一半在65岁之前经历了首次溃疡发作,在静脉溃疡亚组中这一比例更高(61%,P < 0.0001)。静脉溃疡患者溃疡素质的中位持续时间显著长于非静脉病变患者(13.4年对2.5年,P < 0.001)。约一半的静脉溃疡和非静脉溃疡患者当前的溃疡病程超过1年。静脉溃疡比非静脉型溃疡更常复发(患者比例分别为72%和45%,P < 0.0001)。静脉溃疡患者的体重指数显著更高(P < 0.001)。每周每10万人口进行的换药次数为1100次。静脉溃疡“经典”临床指标的预测价值不超过0.76。为提高静脉溃疡诊断的准确性,临床检查应与静脉循环无创“客观”血流动力学评估相结合。

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