Kotagal S, Gibbons V P, Stith J A
Department of Neurology, Saint Louis University Medical Center, MO 63110.
Dev Med Child Neurol. 1994 Apr;36(4):304-11. doi: 10.1111/j.1469-8749.1994.tb11850.x.
The all-night polysomnographic findings of nine patients with spastic quadriparesis (mean age 36.7 months) were analysed retrospectively and compared with those of nine age-matched controls (mean age 37.4 months). The cerebral palsy group had significantly more respiratory disturbances per hour of sleep, with five of nine being diagnosed as having obstructive sleep apnea. They also had fewer changes in body position during the night. Interictal epileptiform discharges averaged 23.3 per cent of the total arousals in the cerebral palsy group. Obstructive apnea, decreased ability to change body position, and interictal epileptiform discharges are prevalent in the sleep of patients with severe cerebral palsy, and contribute towards its disruption.
回顾性分析了9例痉挛性四肢瘫患者(平均年龄36.7个月)的整夜多导睡眠图结果,并与9例年龄匹配的对照者(平均年龄37.4个月)进行比较。脑瘫组每小时睡眠中的呼吸障碍明显更多,9例中有5例被诊断为阻塞性睡眠呼吸暂停。他们夜间身体姿势的变化也较少。脑瘫组发作间期癫痫样放电平均占总觉醒次数的23.3%。阻塞性呼吸暂停、身体姿势改变能力下降和发作间期癫痫样放电在重度脑瘫患者睡眠中普遍存在,并导致睡眠中断。