Selvadurai Sarah, Voutsas Giorge, Propst Evan J, Wolter Nikolaus E, Narang Indra
Division of Respiratory Medicine, Hospital for Sick Children, Toronto, Ontario.
University of Toronto, Toronto, Ontario.
Paediatr Child Health. 2019 Jul 10;25(7):432-438. doi: 10.1093/pch/pxz097. eCollection 2020 Nov.
Undiagnosed and untreated obstructive sleep apnea (OSA) can predispose children to neurobehavioural consequences. However, there is a lack of data identifying rate of, and risk factors for, OSA in very young healthy children. The objective of this study was to determine the rate of OSA and identify risk factors associated with the presence and severity of OSA in children aged 3 years and younger.
This was a retrospective chart review of healthy children between 1 and 3 years old who had a baseline polysomnogram (PSG) between January 2012 and June 2017. Patient demographics, referral history, and PSG data were recorded.
One hundred and thirteen children were referred for a PSG, of which 66 (58%) were diagnosed with OSA and 47 (42%) did not have OSA. In the OSA group, 13 (20%) were mild and 53 (80%) were moderate-severe. Nasal congestion (P=0.001), adenoid hypertrophy (P=<0.001), and tonsillar hypertrophy (P=0.04) reported at the time of referral were more common in the OSA group compared to the no-OSA group. Binary logistic regression analysis showed that referral from an otolaryngologist (odds ratio=2.6, 95% confidence interval=1.1 to 6.0) were associated with moderate-severe OSA.
A high rate of OSA was found among children aged 3 years and younger. Children referred by an otolaryngologist are more likely to be diagnosed with moderate-severe OSA. Children aged 3 years and younger with symptoms of OSA should be considered high-risk for OSA and be prioritized for early PSG and management.
未诊断和未治疗的阻塞性睡眠呼吸暂停(OSA)会使儿童易出现神经行为方面的后果。然而,目前缺乏关于非常年幼健康儿童中OSA的发生率及危险因素的数据。本研究的目的是确定3岁及以下儿童中OSA的发生率,并识别与OSA的存在及严重程度相关的危险因素。
这是一项对2012年1月至2017年6月期间进行了基线多导睡眠图(PSG)检查的1至3岁健康儿童的回顾性病历审查。记录了患者的人口统计学信息、转诊史和PSG数据。
113名儿童被转诊进行PSG检查,其中66名(58%)被诊断为OSA,47名(42%)未患OSA。在OSA组中,13名(20%)为轻度,53名(80%)为中重度。与无OSA组相比,转诊时报告的鼻塞(P=0.001)、腺样体肥大(P<0.001)和扁桃体肥大(P=0.04)在OSA组中更为常见。二元逻辑回归分析显示,来自耳鼻喉科医生的转诊(比值比=2.6,95%置信区间=1.1至6.0)与中重度OSA相关。
在3岁及以下儿童中发现了较高的OSA发生率。由耳鼻喉科医生转诊的儿童更有可能被诊断为中重度OSA。3岁及以下有OSA症状的儿童应被视为OSA的高危人群,并应优先进行早期PSG检查和治疗。