Maniar B M
Goculdas Tejpal Hospital, Bombay.
Indian J Pediatr. 1993 Sep-Oct;60(5):659-67. doi: 10.1007/BF02821729.
A prospective study was conducted on 185 consecutive hospitalized cases of tuberculosis below the age of one year, and 41 mothers comprised half of the 83 contacts detected. Maternal and infant infection was analyzed to determine whether the disease could have been prevented under the existing medico-socio-economic conditions. Most mothers had delayed diagnosis and extensive disease. Earlier imperfect courses of chemotherapy were not uncommon. Ten mothers were sputum-positive for acid-fast bacilli. The concerned medical personnel failed to give proper advice with respect to chemoprophylaxis and surveillance of infants. Majority of infants had progressive pulmonary and disseminated disease although, 41% of them were BCG vaccinated. A practical strategy in the Indian context for the management of tuberculosis in the mother-infant pair is outlined.
对185例年龄在一岁以下的连续住院结核病病例进行了一项前瞻性研究，在检测出的83名接触者中，41名母亲占了一半。对母婴感染情况进行了分析，以确定在现有的医疗社会经济条件下该病是否可以预防。大多数母亲诊断延迟且病情广泛。早期化疗疗程不完善的情况并不少见。10名母亲痰涂片抗酸杆菌阳性。相关医务人员未就婴儿的化学预防和监测提供适当建议。尽管41%的婴儿接种了卡介苗，但大多数婴儿仍患有进行性肺部疾病和播散性疾病。本文概述了印度背景下母婴结核病管理的实用策略。
