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由化脓性链球菌引起的快速致死性坏死性筋膜炎。

Rapidly fatal necrotising fasciitis caused by Streptococcus pyogenes.

作者信息

Donaldson P M, Naylor B, Lowe J W, Gouldesbrough D R

机构信息

Department of Clinical medicine, University of Leeds.

出版信息

J Clin Pathol. 1993 Jul;46(7):617-20. doi: 10.1136/jcp.46.7.617.

Abstract

AIMS

To describe the morbid anatomical and bacteriological features in a series of five cases of rapidly fatal Streptococcus pyogenes necrotising fasciitis.

METHODS

Post mortem and bacteriological examinations were made of five patients dying within 48 hours from rapidly fatal necrotising fasciitis.

RESULTS

All five cases died rapidly from a toxic Streptococcus toxin syndrome as a result of developing necrotising fasciitis following trivial injury.

CONCLUSIONS

Necrotising fasciitis caused by Streptococcus pyogenes infection can be rapidly fatal. This is probably the result of a toxic shock syndrome. Rapid, early diagnosis and swift and probably empirical treatment is required to avoid a fatal outcome.

摘要

目的

描述一系列5例快速致死性化脓性链球菌坏死性筋膜炎病例的病态解剖学和细菌学特征。

方法

对5例在48小时内死于快速致死性坏死性筋膜炎的患者进行尸检和细菌学检查。

结果

所有5例均因轻微损伤后发生坏死性筋膜炎,迅速死于中毒性链球菌毒素综合征。

结论

化脓性链球菌感染引起的坏死性筋膜炎可迅速致死。这可能是中毒性休克综合征的结果。需要快速、早期诊断以及迅速且可能是经验性的治疗,以避免致命后果。

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引用本文的文献

本文引用的文献

1
Six Cases of Acute Infective Gangrene of the Extremities.6例急性肢体感染性坏疽
Proc R Soc Med. 1909;2(Clin Sect):213-8. doi: 10.1177/003591570900200178.
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Arch Surg. 1962 Dec;85:969-73. doi: 10.1001/archsurg.1962.01310060105019.
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Fatal streptococcal septicaemia.致死性链球菌败血症
Br Med J (Clin Res Ed). 1981 Jun 13;282(6280):1944-5. doi: 10.1136/bmj.282.6280.1944.
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Necrotizing fasciitis.坏死性筋膜炎
Ann Surg. 1970 Dec;172(6):957-64. doi: 10.1097/00000658-197012000-00005.

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