Courtright J B
Mol Gen Genet. 1975 Dec 30;142(3):231-8. doi: 10.1007/BF00425648.
A phenotypic effect of the lxd locus in the expression of the cin and ma-l gene products has been described. Flies which are genotypically lxd have normal eye pigments, but maternally affected cin; lxd or ma-l; lxd flies are characterized by mutant eyes which are indistinguishable from those observed in ma-l or ry mutant strains. Furthermore, under ocnditions where there is only partial complementation at the ma-l locus, the presence of the lxd gene is sufficient to prevent normal eye pigmentation. The possibility that these post translational interactions of the cin, lxd, and ma-l loci may prove useful in the isolation of additional loci affecting XDH synthesis is discussed.
已描述了lxd基因座在cin和ma-l基因产物表达中的表型效应。基因型为lxd的果蝇具有正常的眼色素，但母体受影响的cin；lxd或ma-l；lxd果蝇的特征是突变眼，与在ma-l或ry突变株中观察到的突变眼无法区分。此外，在ma-l基因座仅存在部分互补的情况下，lxd基因的存在足以阻止正常的眼色素沉着。讨论了cin、lxd和ma-l基因座的这些翻译后相互作用在分离影响XDH合成的其他基因座方面可能有用的可能性。
