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New cycloartanol sulfates from the alga Tydemania expeditionis: inhibitors of the protein tyrosine kinase pp60v-src.

作者信息

Govindan M, Abbas S A, Schmitz F J, Lee R H, Papkoff J S, Slate D L

机构信息

Department of Chemistry and Biochemistry, University of Oklahoma, Norman 73019.

出版信息

J Nat Prod. 1994 Jan;57(1):74-8. doi: 10.1021/np50103a010.

DOI:10.1021/np50103a010
PMID:8158167
Abstract

Bioactivity-directed fractionation of the extracts of the green alga Tydemania expeditionis using the protein tyrosine kinase pp60v-src led to the isolation of three new cycloartanol disulfates, 1-3, which show modest inhibition of this enzyme. The structures were deduced by spectroscopic methods.

摘要

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