Ferner R E, Whittington R M
Dudley Road Hospital, Birmingham, UK.
J R Soc Med. 1994 Mar;87(3):145-8. doi: 10.1177/014107689408700311.
The records for Coroner's Inquests in one district during a 6 year period were examined retrospectively to establish the number and nature of deaths which were due to errors in the prescription or administration of medicines, and those due to adverse drug reactions. The district has a population of 1.19 million (1991), and a total of 3277 inquests were opened during the period 1986-1991. Ten of the deaths were identified as due to errors of prescribing or giving drugs. During the same period, 36 deaths were caused by adverse drug reactions. These 46 deaths made up approximately one in 2000 of all deaths during the study period. About a fifth of deaths related to prescribing and administering drugs are due to errors and may be more easily preventable than deaths due to adverse reactions.
对某地区六年期间死因裁判法庭的记录进行了回顾性审查,以确定因药物处方或用药错误导致的死亡数量和性质,以及因药物不良反应导致的死亡情况。该地区在1991年有119万人口,在1986 - 1991年期间共开启了3277次死因调查。其中有10例死亡被认定为因开药或给药错误所致。在同一时期,有36例死亡是由药物不良反应引起的。这46例死亡约占研究期间所有死亡人数的两千分之一。与开药和用药相关的死亡中,约五分之一是由错误导致的,相较于因不良反应导致的死亡,这类死亡可能更容易预防。