Uzoaru I, Chou P, Reyes-Mugica M
Department of Pathology, Children's Memorial Hospital, Northwestern University, Chicago, Illinois 60614.
Pediatr Pathol. 1994 Jan-Feb;14(1):11-8. doi: 10.3109/15513819409022021.
We describe a case of malignant solitary fibrous tumor of the pleura in a 15-year-old female who presented clinically with back pain. Grossly, the tumor had a pedicle attached to the pleura and histologically showed proliferating spindle-shaped cells with a high mitotic index. Immunohistochemical and ultrastructural features were consistent with a tumor of fibroblastic origin. Flow cytometric DNA analysis revealed an aneuploid population among the tumor cells.