Rodríguez Leal G A, Jiménez Torres R, Lome C, Pérez Alvarado N, Muñoz Fernández L, Vargas Rodríguez A
Departamento de Gastroenterología, Instituto Nacional de la Nutrición Salvador Zubirán, México, D.F.
Rev Gastroenterol Mex. 1993 Oct-Dec;58(4):359-65.
Solitary rectal ulcer syndrome (SRUS) is an unusual disorder which is seldom seen in our hospital. Considerable uncertainly remains concerning the cause, natural history, and management of this condition. During 1980-1992 period, 7 patients were seen at the Instituto Nacional de la Nutrición and the diagnosis was established on histological, sigmoidoscopic and clinical grounds. Most of the patients suffered rectal bleeding, abdominal pain, straining at defecation, tenemus and rectal mucus discharge. Laboratory results were non specific. Eighty-five percent has macroscopic ulcerations and these were found within 5.2 cm of the anal margin and usually situated anteriorly. Neither medical nor local surgical treatment consistently achieved relief of symptoms or healing of the lesion.
孤立性直肠溃疡综合征（SRUS）是一种罕见的疾病，在我院很少见。关于这种疾病的病因、自然史和治疗方法仍存在相当大的不确定性。在1980年至1992年期间，国立营养研究所共诊治了7例患者，诊断基于组织学、乙状结肠镜检查和临床依据。大多数患者有直肠出血、腹痛、排便时用力、里急后重和直肠黏液排出。实验室检查结果无特异性。85%的患者有肉眼可见的溃疡，这些溃疡位于距肛缘5.2厘米范围内，且通常位于前方。药物治疗和局部手术治疗均未能持续缓解症状或治愈病变。
