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[脂质体对挤压综合征时心脏和肝脏脂质过氧化的影响]

[Effect of liposomes on lipid peroxidation in the heart and liver in crush syndrome].

作者信息

El'skiĭ V N, Stefanov A V, Mareeva T E, Kolesnikova S V, Skobeleva E I, Kas'ianova E V

出版信息

Ukr Biokhim Zh (1978). 1993 Sep-Oct;65(5):109-12.

PMID:8160290
Abstract

The increased lipid peroxidation has been determined to be one of general mechanisms of disturbance in the functional state of the heart and liver fraction cells, regularities of inter-system disturbance in metabolic activity under the crush syndrome have been revealed. Administration of lecithin liposomes results in the decreased POL levels, increased antioxidant capacity of the organism. That permits recommending to include liposomes into complex therapeutics of the crush syndrome as detoxicating, antiinflammatory and antihypoxic drug.

摘要

脂质过氧化增加已被确定为心脏和肝脏部分细胞功能状态紊乱的一般机制之一,已揭示挤压综合征下代谢活动中系统间紊乱的规律。给予卵磷脂脂质体可降低POL水平,提高机体抗氧化能力。这使得可以推荐将脂质体纳入挤压综合征的综合治疗中,作为解毒、抗炎和抗缺氧药物。

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