甲状腺切除术及给予三碘甲状腺原氨酸对大鼠空肠上皮细胞增殖的影响。
The influence of thyroidectomy and of triiodothyronine administration on epithelial cell proliferation in the jejunum of rat.
作者信息
Tutton P J
出版信息
Virchows Arch B Cell Pathol. 1976 Mar 9;20(2):139-42. doi: 10.1007/BF02890334.
PMID:816074
Abstract
Mitotic rates in epithelial cells lining the bases of the crypts of Lieberkühn in rat jejunum were measured using a stathmokinetic technique. Two weeks after surgical thyroidectomy the mitotic rate in the jejunal crypt cells was significantly lower than that in control animals. During the four hour period immediately after injection of triiodothyronine into thyroidectomized rats the crypt cell mitotic rate was significantly higher than in control animals.
摘要
采用有丝分裂阻断技术测定大鼠空肠利伯孔隐窝底部上皮细胞的有丝分裂率。甲状腺切除术后两周，空肠隐窝细胞的有丝分裂率显著低于对照动物。在给甲状腺切除的大鼠注射三碘甲状腺原氨酸后的4小时内，隐窝细胞有丝分裂率显著高于对照动物。
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