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用红霉素根除解脲脲原体成功治疗早产。

Successful treatment of preterm labour by eradication of Ureaplasma urealyticum with erythromycin.

作者信息

Mazor M, Chaim W, Horowitz S, Leiberman J R, Glezerman M

机构信息

Department of Obstetrics and Gynecology, Soroka Medical Center of Kupat Holim, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

Arch Gynecol Obstet. 1993;253(4):215-8. doi: 10.1007/BF02766648.

DOI:10.1007/BF02766648
PMID:8161256
Abstract

Ureaplasma urealyticum was detected in the amniotic cavity of a woman with premature contractions at 32 weeks of pregnancy. Treatment with Erythromycin base was instituted for a period of ten days. Amniotic fluid analysis performed 48 hours after discontinuation of antibiotic treatment revealed sterile amniotic fluid. The pregnancy continued uneventfully until 39 weeks.

摘要

在一名怀孕32周出现早产宫缩的女性羊膜腔内检测到解脲脲原体。给予红霉素碱治疗十天。抗生素治疗停止48小时后进行的羊水分析显示羊水无菌。妊娠顺利持续至39周。

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本文引用的文献

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Harefuah. 1993 Apr 15;124(8):500-5.
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Standardized method for determining antimicrobial susceptibility of strains of Ureaplasma urealyticum and their response to tetracycline, erythromycin, and rosaramicin.解脲脲原体菌株抗菌药敏性测定的标准化方法及其对四环素、红霉素和罗沙米星的反应
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Ureaplasma urealyticum incriminated in perinatal morbidity and mortality.
抗生素的应用可以消除一部分胎膜完整的早产患者的羊膜内感染或羊膜内炎症。
Am J Obstet Gynecol. 2019 Aug;221(2):142.e1-142.e22. doi: 10.1016/j.ajog.2019.03.018. Epub 2019 Mar 27.
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The Human Ureaplasma Species as Causative Agents of Chorioamnionitis.人脲原体作为绒毛膜羊膜炎的病原体
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Gastric fluid versus amniotic fluid analysis for the identification of intra-amniotic infection due to Ureaplasma species.胃液与羊水分析用于鉴定解脲脲原体引起的羊膜腔内感染。
J Matern Fetal Neonatal Med. 2016;29(16):2579-87. doi: 10.3109/14767058.2015.1098614. Epub 2015 Dec 2.
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A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM.一种新的抗菌组合可延长潜伏期,减少急性组织学绒毛膜羊膜炎以及脐带炎,并改善早产胎膜早破的新生儿结局。
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A novel molecular microbiologic technique for the rapid diagnosis of microbial invasion of the amniotic cavity and intra-amniotic infection in preterm labor with intact membranes.一种用于快速诊断胎膜完整的早产患者羊膜腔微生物入侵和羊膜腔内感染的新型分子微生物学技术。
Am J Reprod Immunol. 2014 Apr;71(4):330-58. doi: 10.1111/aji.12189. Epub 2014 Jan 13.
8
Transplacental transfer of Azithromycin and its use for eradicating intra-amniotic ureaplasma infection in a primate model.阿奇霉素的胎盘转运及其在灵长类动物模型中消除羊膜腔内脲原体感染的应用。
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解脲脲原体与围产期发病率和死亡率有关。
Science. 1981 Jul 24;213(4506):474-5. doi: 10.1126/science.7244646.
4
Isolation of Mycoplasma hominis and Ureaplasma urealyticum from amniotic fluid at 16-20 weeks of gestation: potential effect on outcome of pregnancy.妊娠16 - 20周时从羊水分离人型支原体和解脲脲原体:对妊娠结局的潜在影响。
Sex Transm Dis. 1983 Oct-Dec;10(4 Suppl):294-302.
5
Enhancing effect on alkalinization of the medium on the activity of erythromycin against gram-negative bacteria.对培养基碱化对红霉素抗革兰氏阴性菌活性的增强作用。
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6
Use of parenteral antibiotic therapy to eradicate bacterial colonization of amniotic fluid in premature rupture of membranes.使用胃肠外抗生素疗法根除胎膜早破时羊水的细菌定植。
Obstet Gynecol. 1986 Mar;67(3 Suppl):15S-17S. doi: 10.1097/00006250-198603001-00005.
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Effect on birth weight of erythromycin treatment of pregnant women.红霉素治疗孕妇对出生体重的影响。
Obstet Gynecol. 1987 Feb;69(2):202-7.
8
Intraamniotic infection and the onset of labor in preterm premature rupture of the membranes.羊膜腔内感染与胎膜早破早产时的分娩发动
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Infection and preterm labor.感染与早产
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Association of Ureaplasma urealyticum infection of the lower respiratory tract with chronic lung disease and death in very-low-birth-weight infants.极低出生体重儿下呼吸道解脲脲原体感染与慢性肺病及死亡的关联
Lancet. 1988 Jul 30;2(8605):240-5. doi: 10.1016/s0140-6736(88)92536-6.