由于细丝滑动导致粗丝缩短
[Thick filament shortening as a result of filament sliding].
作者信息
Sidorenko N P, Klimov A A
出版信息
Biofizika. 1994 Jan-Feb;39(1):153-5.
PMID:8161585
Abstract
It is usually accepted that the phenomenon of thick filament shortening contradicts the sliding filament theory and cross-bridge mechanism of force generation. However, some peculiarity of experimental data indicate the thick filament shortening can be a corollary of the interaction of myosin cross-bridges with the actin filaments "wrong" polarities in sarcomeres with the actin filaments double overlap formed in the results of the filament sliding.
摘要
通常认为，粗肌丝缩短现象与肌丝滑行理论及力产生的横桥机制相矛盾。然而，实验数据的一些特性表明，粗肌丝缩短可能是肌球蛋白横桥与肌动蛋白丝相互作用的必然结果，这种相互作用发生在肌节中肌动蛋白丝具有“错误”极性且因肌丝滑行而形成肌动蛋白丝双重重叠的情况下。
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