Supparatpinyo K, Sirisanthana T
Faculty of Medicine, Chiang Mai University, Thailand.
Clin Infect Dis. 1994 Feb;18(2):246-7. doi: 10.1093/clinids/18.2.246.
We describe a case of disseminated Penicillium marneffei infection in a patient infected with human immunodeficiency virus. The diagnosis was made by examination of a peripheral blood smear. The patient presented with fever, jaundice, generalized lymphadenopathy, hepatosplenomegaly, and an erythematous, papular rash. Microscopic examination of a Wright's-stained peripheral blood smear revealed many yeast cells in neutrophils. Some yeast cells had clear central septation. Presumptive diagnosis of disseminated P. marneffei infection was made, and treatment was started several days before the culture results were available.
我们描述了一例感染人类免疫缺陷病毒的患者发生播散性马尔尼菲青霉感染的病例。诊断通过外周血涂片检查做出。该患者表现为发热、黄疸、全身淋巴结肿大、肝脾肿大以及红斑丘疹性皮疹。对经瑞氏染色的外周血涂片进行显微镜检查发现中性粒细胞中有许多酵母细胞。一些酵母细胞有清晰的中央分隔。做出了播散性马尔尼菲青霉感染的初步诊断，并在培养结果出来前几天就开始了治疗。
