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阿曼晚期HIV患者中的输入性嗜热栖热放线菌病:流行区以外的诊断挑战

Imported Talaromycosis in Oman in Advanced HIV: A Diagnostic Challenge Outside the Endemic Areas.

作者信息

Mohsin Jalila, Khalili Sulin Al, van den Ende A H G Gerrits, Khamis Faryal, Petersen Eskild, de Hoog G Sybren, Meis Jacques F, Al-Hatmi Abdullah M S

机构信息

Department of Medical Microbiology, Royal Hospital, Muscat, Oman.

Westerdijk Fungal Biodiversity Institute, PO Box 85167, 3508 AD, Utrecht, The Netherlands.

出版信息

Mycopathologia. 2017 Aug;182(7-8):739-745. doi: 10.1007/s11046-017-0124-x. Epub 2017 Mar 4.

DOI:10.1007/s11046-017-0124-x
PMID:28260132
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5500679/
Abstract

A 37-year-old male living in Oman was seen by his physician with complaints of cough, body aches with bilateral lower limb weakness and on and off fever. He was diagnosed with HIV infection and culture from blood and bone marrow grew Talaromyces marneffei. He had travelled to Malaysia on several occasions. Treatment with liposomal amphotericin B resulted in complete cure. This case is reported for its rarity and unusual presentation to alert clinicians and microbiologists to consider T. marneffei as an etiology in high risk individuals. Our case is the first recorded diagnosis of T. marneffei in Oman.

摘要

一名居住在阿曼的37岁男性因咳嗽、全身疼痛伴双下肢无力及反复发热就诊于医生。他被诊断为HIV感染,血液和骨髓培养出马尔尼菲篮状菌。他曾多次前往马来西亚。脂质体两性霉素B治疗后完全治愈。报道该病例是因其罕见及不寻常的表现,以提醒临床医生和微生物学家在高危个体中考虑马尔尼菲篮状菌作为病因。我们的病例是阿曼首例有记录的马尔尼菲篮状菌诊断病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0876/5500679/a7b833c14077/11046_2017_124_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0876/5500679/271a6819f84a/11046_2017_124_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0876/5500679/a7b833c14077/11046_2017_124_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0876/5500679/271a6819f84a/11046_2017_124_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0876/5500679/a7b833c14077/11046_2017_124_Fig2_HTML.jpg

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