May C, Carter S D, Bell S C, Bennett D
Department of Veterinary Clinical Science, University of Liverpool.
Br J Rheumatol. 1994 Jan;33(1):27-31. doi: 10.1093/rheumatology/33.1.27.
Measurement of immune complexes, antibodies against canine distemper virus (CDV) and anti-CDV antibodies in immune complexes were made in sera and SF from 'normal' dogs and from dogs with joint diseases. These data were compared with cytological analyses of SF samples. In dogs with canine rheumatoid-like arthritis (CRA) there were correlations between circulating anti-CDV antibody levels and circulating immune complex levels (P < 0.001) and between SF anti-CDV antibody levels and SF immune complex levels (P < 0.01). Furthermore, the SF PMN count in dogs with CRA correlated with both the SF anti-CDV antibody levels (P < 0.001) and the SF immune complex anti-CDV antibody levels (P < 0.001). The results demonstrated a relationship between CDV and ongoing synovial inflammation in dogs with CRA.
对“正常”犬以及患有关节疾病犬的血清和滑液进行免疫复合物、抗犬瘟热病毒（CDV）抗体以及免疫复合物中抗CDV抗体的检测。将这些数据与滑液样本的细胞学分析结果进行比较。在患有类犬类风湿性关节炎（CRA）的犬中，循环抗CDV抗体水平与循环免疫复合物水平之间存在相关性（P < 0.001），滑液抗CDV抗体水平与滑液免疫复合物水平之间也存在相关性（P < 0.01）。此外，患有CRA的犬的滑液中性粒细胞计数与滑液抗CDV抗体水平（P < 0.001）以及滑液免疫复合物抗CDV抗体水平（P < 0.001）均相关。结果表明，CDV与患有CRA的犬的滑膜炎症持续存在之间存在关联。
