Youvan D C
Palo Alto Institute for Molecular Medicine, Mountain View, California 94043.
Nature. 1994 May 5;369(6475):79-80. doi: 10.1038/369079a0.
Digital imaging spectrophotometers can simultaneously measure the spectra of hundreds of features in a two-dimensional scene. While a variety of applications can be anticipated, a colorimetric analysis of mutants expressing pigmented proteins has already led to the development of efficient algorithms for optimizing combinatorial mutagenesis.