Eisenblätter D, Classen E, Schädlich H, Heinemann L
Zentrum für Epidemiologie und Gesundheitsforschung Berlin.
Nervenarzt. 1994 Feb;65(2):95-100.
To determine the incidence rate of stroke, case-fatality within 28 days and diagnostic accuracy in stroke cases in the study population.
Prospective stroke register, including all cases of complete stroke which occurred during 1985-1988 in the population aged 25-64 and 25-74, of 14 districts in East Germany. Case-respectively finding, validation and uniform data collection were carried out by physicians trained to use the WHO-MONICA protocol.
Annual age-standardized event rates were 113 per 100,000 for men and 68/100,000 for women aged 25-64, rates for first-ever stroke were 88/100,000 for men and 52/100,000 for women. For both sexes, incidence and event rates rose exponentially with increasing age. Before age 45 more women than men were affected. 34% of patients aged 25-64 had died by 28 days. Case-fatality in men and women aged 65-74 was higher than in those ten years younger (p < 0.01) and tended to be higher in women. 10% of patients aged 25-64 and 26% of those in the age of 65-74 were treated outside hospital. Before age 65, CT examination and angiography were done in only 18 and 20%, respectively; in elderly patients even less frequently.
The findings suggest that since the 1970s there may have been an increase of stroke incidence in the population of Eastern Germany. The high case-fatality following stroke is confirmed. Evidently there are deficiencies in the medical care of elderly stroke patients.
确定研究人群中中风的发病率、28天内的病死率以及中风病例的诊断准确性。
前瞻性中风登记,包括1985 - 1988年期间在东德14个地区25 - 64岁和25 - 74岁人群中发生的所有完全性中风病例。由经过培训使用世界卫生组织MONICA方案的医生进行病例发现、验证和统一的数据收集。
25 - 64岁男性的年龄标准化年发病率为每10万人113例,女性为每10万人68例;首次中风的发病率男性为每10万人88例,女性为每10万人52例。男女发病率和事件发生率均随年龄增长呈指数上升。45岁之前女性受影响的人数多于男性。25 - 64岁的患者中有34%在28天内死亡。65 - 74岁男性和女性的病死率高于年轻10岁的人群(p < 0.01),且女性病死率往往更高。25 - 64岁的患者中有10%以及65 - 74岁的患者中有26%在院外接受治疗。65岁之前,分别只有18%和20%的患者进行了CT检查和血管造影;老年患者的检查频率更低。
研究结果表明,自20世纪70年代以来,东德人群中风发病率可能有所上升。中风后高病死率得到证实。显然,老年中风患者的医疗护理存在不足。