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[东德人群中风发作的发病率和预后。1985 - 1988年中风登记结果]

[Incidence and prognosis of stroke episodes in the East German population. Results from a stroke register 1985-1988].

作者信息

Eisenblätter D, Classen E, Schädlich H, Heinemann L

机构信息

Zentrum für Epidemiologie und Gesundheitsforschung Berlin.

出版信息

Nervenarzt. 1994 Feb;65(2):95-100.

PMID:8164773
Abstract

OBJECTIVES

To determine the incidence rate of stroke, case-fatality within 28 days and diagnostic accuracy in stroke cases in the study population.

METHODS

Prospective stroke register, including all cases of complete stroke which occurred during 1985-1988 in the population aged 25-64 and 25-74, of 14 districts in East Germany. Case-respectively finding, validation and uniform data collection were carried out by physicians trained to use the WHO-MONICA protocol.

RESULTS

Annual age-standardized event rates were 113 per 100,000 for men and 68/100,000 for women aged 25-64, rates for first-ever stroke were 88/100,000 for men and 52/100,000 for women. For both sexes, incidence and event rates rose exponentially with increasing age. Before age 45 more women than men were affected. 34% of patients aged 25-64 had died by 28 days. Case-fatality in men and women aged 65-74 was higher than in those ten years younger (p < 0.01) and tended to be higher in women. 10% of patients aged 25-64 and 26% of those in the age of 65-74 were treated outside hospital. Before age 65, CT examination and angiography were done in only 18 and 20%, respectively; in elderly patients even less frequently.

CONCLUSIONS

The findings suggest that since the 1970s there may have been an increase of stroke incidence in the population of Eastern Germany. The high case-fatality following stroke is confirmed. Evidently there are deficiencies in the medical care of elderly stroke patients.

摘要

目的

确定研究人群中中风的发病率、28天内的病死率以及中风病例的诊断准确性。

方法

前瞻性中风登记,包括1985 - 1988年期间在东德14个地区25 - 64岁和25 - 74岁人群中发生的所有完全性中风病例。由经过培训使用世界卫生组织MONICA方案的医生进行病例发现、验证和统一的数据收集。

结果

25 - 64岁男性的年龄标准化年发病率为每10万人113例,女性为每10万人68例;首次中风的发病率男性为每10万人88例,女性为每10万人52例。男女发病率和事件发生率均随年龄增长呈指数上升。45岁之前女性受影响的人数多于男性。25 - 64岁的患者中有34%在28天内死亡。65 - 74岁男性和女性的病死率高于年轻10岁的人群(p < 0.01),且女性病死率往往更高。25 - 64岁的患者中有10%以及65 - 74岁的患者中有26%在院外接受治疗。65岁之前,分别只有18%和20%的患者进行了CT检查和血管造影;老年患者的检查频率更低。

结论

研究结果表明,自20世纪70年代以来,东德人群中风发病率可能有所上升。中风后高病死率得到证实。显然,老年中风患者的医疗护理存在不足。

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