Bahal-O'Mara N, Force R W, Nahata M C
College of Pharmacy, Ohio State University, Columbus.
Am Pharm. 1994 Jan;NS34(1):31-5. doi: 10.1016/s0160-3450(15)30540-7.
Although a number of differently flavored antacids have been introduced recently, no blinded comparative palatability evaluations have been conducted since 1977. A comparative, randomized, single-blind evaluation of over-the-counter aluminum and magnesium antacid suspensions was conducted to determine their relative palatability. Thirty healthy volunteers were asked to evaluate 14 antacids for smell, taste, texture, and aftertaste. The study found a statistically significant difference in all rated characteristics of antacids. Mylanta Cherry Creme (score 24.4 out of possible 36) and Mylanta Double Strength Cool Mint Creme (score 24.2) were ranked highest in overall palatability; Riopan Plus 2 (score 18.7) and Di-Gel Lemon Orange (score 18.0) were ranked lowest. The study concluded that the palatability of various antacid suspensions differs markedly and should be considered when selecting an antacid product.
尽管最近推出了多种不同口味的抗酸剂，但自1977年以来，尚未进行过盲法比较适口性评估。对非处方铝和镁抗酸剂混悬液进行了一项比较、随机、单盲评估，以确定它们的相对适口性。30名健康志愿者被要求对14种抗酸剂的气味、味道、质地和余味进行评估。研究发现，抗酸剂所有评级特征在统计学上均存在显著差异。胃得乐樱桃奶油味（满分36分，得24.4分）和胃得乐双倍强度清凉薄荷味（24.2分）在总体适口性方面排名最高；乐得胃加强2号（18.7分）和迪吉尔柠檬橙子味（18.0分）排名最低。该研究得出结论，各种抗酸剂混悬液的适口性差异显著，在选择抗酸剂产品时应予以考虑。
