Cole F H, Thomas J E, Wilcox A B, Halford H H
Department of Radiology, Methodist Hospitals of Memphis, Tennessee.
Ann Thorac Surg. 1994 Apr;57(4):838-40. doi: 10.1016/0003-4975(94)90185-6.
The issue of screening for cerebral metastatic disease in the preoperative bronchogenic carcinoma patient remains unsettled and changes with advancing technology. A prospective nonrandomized study was designed to compare contrast magnetic resonance imaging (MRI) with computed tomography (CT) after several clinical situations suggested improved sensitivity for the former study. Patients with clinically operable disease and normal neurologic examinations were referred for both enhanced cerebral CT and MRI studies. Forty-two patients were entered and completed the enhanced CT scan; only 30 tolerated the MRI. The demographic data and histology of the patients appeared fairly typical for a series of operative candidates. No unsuspected metastatic lesion was found in this selected and low-risk group. We conclude that neither MRI nor enhanced CT scan is indicated in the asymptomatic bronchogenic carcinoma patient due to expense and lack of positive findings. Magnetic resonance imaging demonstrated more subtle benign pathology, but this study did not allow comparison of the two techniques in detection of metastatic disease.
术前支气管源性癌患者的脑转移疾病筛查问题仍未解决，且随着技术进步而变化。在几种临床情况提示对比磁共振成像（MRI）敏感性更高之后，设计了一项前瞻性非随机研究，以比较对比MRI与计算机断层扫描（CT）。临床可手术且神经系统检查正常的患者接受增强脑CT和MRI检查。42例患者进行并完成了增强CT扫描；只有30例耐受了MRI检查。患者的人口统计学数据和组织学对于一系列手术候选者来说似乎相当典型。在这个经过挑选的低风险组中未发现意外的转移病灶。我们得出结论，由于费用和缺乏阳性发现，无症状支气管源性癌患者既不需要MRI也不需要增强CT扫描。磁共振成像显示出更细微的良性病变，但本研究无法比较这两种技术在检测转移疾病方面的情况。
