Cramer L P, Mitchison T J, Theriot J A
Department of Pharmacology, University of California, San Francisco 94143-0450.
Curr Opin Cell Biol. 1994 Feb;6(1):82-6. doi: 10.1016/0955-0674(94)90120-1.
Force arising from actin polymerization and myosin activity drives a number of different actin-based cell movements. Several new reports support previous data suggesting that actin polymerization drives lamellipodial protrusion and bacterial propulsion, and one report describes a more indirect role for actin assembly in axonal elongation. The major new findings of the past year concerning possible motility roles for myosin describe myosin-driven protrusion of cell margins.
由肌动蛋白聚合和肌球蛋白活性产生的力驱动了许多基于肌动蛋白的不同细胞运动。几篇新报告支持了先前的数据，这些数据表明肌动蛋白聚合驱动片状伪足突出和细菌推进，并且有一篇报告描述了肌动蛋白组装在轴突伸长中发挥的更间接作用。过去一年中关于肌球蛋白可能的运动作用的主要新发现描述了肌球蛋白驱动的细胞边缘突出。
