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[发育中的中耳表皮样形成及其与先天性胆脂瘤的关系]

[Epidermoid formation in the developing middle ear and its relationship to congenital cholesteatoma].

作者信息

Huang J M

机构信息

First Affiliated Hospital of Fujian Medical College, Fuzhou.

出版信息

Zhonghua Er Bi Yan Hou Ke Za Zhi. 1993;28(4):228-30, 252-3.

PMID:8167044
Abstract

Forty-nine fetuses, ranging from 12 weeks to full term of fetal age, were collected to study the epidermoid formation(EF) in the middle ear. The results showed that: 1) Sixteen of 49 fetuses had EFs in the middle ear aged 14 to 38 weeks of gestation. The structure always appeared between the anterosuperior edge of the eardrum and the anterior limb of the tympanic ring. The width and height of the EFs were 60.82 +/- 5.68 microns and 45.87 +/- 6.82 microns respectively. 2) The EFs might be classified into two types: simple EF and hyperplastic EF. Most of the simple EFs would degenerate and disappear in the late fetal stage, but a few of them might transform into hyperplastic ones. The hyperplastic EF showed more active appearance and multilayered structure, so it seemed to grow continuously, and might develop into congenital cholesteatoma.

摘要

收集了49例胎龄从12周直至足月的胎儿,以研究中耳表皮样形成(EF)。结果显示:1)49例胎儿中有16例在妊娠14至38周时中耳存在表皮样形成。该结构总是出现在鼓膜前上缘与鼓环前肢之间。表皮样形成的宽度和高度分别为60.82±5.68微米和45.87±6.82微米。2)表皮样形成可分为两种类型:单纯型表皮样形成和增生型表皮样形成。大多数单纯型表皮样形成在胎儿后期会退化消失,但少数可能转变为增生型。增生型表皮样形成外观更活跃且呈多层结构,因此似乎会持续生长,并可能发展为先天性胆脂瘤。

相似文献

1
[Epidermoid formation in the developing middle ear and its relationship to congenital cholesteatoma].[发育中的中耳表皮样形成及其与先天性胆脂瘤的关系]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1993;28(4):228-30, 252-3.
2
An epidermoid formation in the developing middle ear: possible source of cholesteatoma.发育中的中耳内的表皮样结构:胆脂瘤的可能来源。
J Otolaryngol. 1986 Jun;15(3):169-74.
3
Congenital cholesteatomas in children: an embryologic correlation.儿童先天性胆脂瘤:胚胎学关联
Laryngoscope. 1988 Sep;98(9):949-55. doi: 10.1288/00005537-198809000-00008.
4
[Altered cytokeratin expression of the epidermoid formation in the tympanic cavity of human fetuses].[人胎儿鼓室表皮样形成中细胞角蛋白表达的改变]
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1996;31(2):72-4.
5
Origin of congenital cholesteatoma from a normally occurring epidermoid rest in the developing middle ear.先天性胆脂瘤起源于发育中的中耳内正常存在的表皮样残余组织。
Int J Pediatr Otorhinolaryngol. 1988 Feb;15(1):51-65. doi: 10.1016/0165-5876(88)90050-x.
6
Congenital cholesteatomas of the middle ear in children: origin and management.儿童中耳先天性胆脂瘤:起源与治疗
Otolaryngol Clin North Am. 1989 Oct;22(5):941-54.
7
Bilateral congenital middle ear cholesteatomas.双侧先天性中耳胆脂瘤
Laryngoscope. 1984 Nov;94(11 Pt 1):1461-3.
8
"Congenital cholesteatoma" of the middle ear. A report of 11 cases.中耳“先天性胆脂瘤”。11例报告。
Am J Otol. 1984 Jul;5(5):368-73.
9
[Congenital cholesteatoma of the middle ear in children].[儿童中耳先天性胆脂瘤]
Rev Laryngol Otol Rhinol (Bord). 1992;113(1):7-10.
10
[Cholesteatoma of the middle ear with closed tympanic membrane in children. Apropos of 8 cases].[儿童中耳胆脂瘤伴鼓膜封闭。附8例报告]
Ann Otolaryngol Chir Cervicofac. 1993;110(5):247-54.

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