Poët J L, Garnier P P, Tonolli-Serabian I, Mattei J P, Gauthier A, Roux H
Service de Rhumatologie, Hôpital de la Conception, Marseille.
Rev Rhum Ed Fr. 1993 Apr;60(4):305-7.
The authors report a patient with concomitant Sjögren's syndrome and chronic hepatitis C. Close associations between autoimmune liver disease, chronic hepatitis C, and Sjögren's syndrome have been demonstrated. The most likely hypothesis involves triggering of an autoimmune cascade by the hepatitis C virus. Prevalence of hepatitis C virus infection in patients with Sjögren's syndrome and potential therapeutic implications of this disease combinations remain to be determined.
作者报告了一例同时患有干燥综合征和慢性丙型肝炎的患者。自身免疫性肝病、慢性丙型肝炎和干燥综合征之间的密切关联已得到证实。最有可能的假说是丙型肝炎病毒引发自身免疫级联反应。干燥综合征患者中丙型肝炎病毒感染的患病率以及这种疾病组合的潜在治疗意义仍有待确定。