Ghali W A, Palepu A, Paterson W G
Department of Medicine, Queen's University, Kingston, Ont.
CMAJ. 1994 May 1;150(9):1449-54.
To assess current red blood cell (RBC) transfusion practices and to determine the potential impact of implementing recently published guidelines on RBC transfusion from the American College of Physicians (ACP).
Medical chart review.
A 219-bed teaching hospital in Kingston, Ont.
All patients over 12 years of age who received RBC transfusions in March 1992.
Need for transfusion according to the ACP guidelines and the number of blood units ordered for each transfusion.
A total of 55 patients received 170 RBC units. According to the ACP guidelines 94 (55.3%) of the units were judged unnecessary. The departments of Surgery and Internal Medicine did not differ significantly in the number of unnecessary units (56.4% v. 52.8%). Among the surgical subspecialties, unnecessary transfusion was most common in the orthopedics service (73.5%, p < 0.05). Blood was most frequently ordered 2 units at a time (51.8% of units). Transfusion in normovolemic, hemodynamically stable patients with anemia and unnecessary multiple-unit transfusions were the most common violations of the ACP guidelines.
According to the ACP guidelines, there was significant unnecessary blood use in the hospital surveyed. The guidelines provide a useful framework for assessing transfusion practices but may require further refinement to apply to a broader spectrum of clinical settings.
评估当前红细胞(RBC)输血实践,并确定实施美国医师协会(ACP)最近发布的RBC输血指南可能产生的影响。
病历审查。
安大略省金斯顿一家拥有219张床位的教学医院。
1992年3月接受RBC输血的所有12岁以上患者。
根据ACP指南确定的输血需求以及每次输血所订购的血液单位数量。
共有55名患者接受了170个RBC单位的输血。根据ACP指南,94个(55.3%)单位被判定为不必要。外科和内科的不必要单位数量没有显著差异(56.4%对52.8%)。在外科亚专业中,不必要输血在骨科最常见(73.5%,p<0.05)。每次最常订购2个单位的血液(占单位数的51.8%)。对血容量正常、血流动力学稳定的贫血患者进行输血以及不必要的多单位输血是最常见的违反ACP指南的情况。
根据ACP指南,在所调查的医院中存在大量不必要的血液使用情况。这些指南为评估输血实践提供了一个有用的框架,但可能需要进一步完善以适用于更广泛的临床环境。