Tomsíková A
Ustav mikrobiologie a imunologie, Lékarská fakulta Univerzity Karlovy, Plzen.
Cesk Epidemiol Mikrobiol Imunol. 1994 Mar;43(1):23-5.
The typical clinical picture and mycological and histological basis of chromomycosis is compared with the clinical course, which is encountered more often nowadays. It refers also to the affection of the vascular, respiratory, lymphatic system, the brain and the dissemination in compromised patients. For this reason chromomycosis should rank among opportunistic mycoses. Chromohyphomycosis characterized by skin nodules occurs very rarely. Subcutaneous abscesses also called phaeomycotic cysts, are more frequent especially after corticoid and immunosuppressive therapy. Among three Czechoslovak cases of chromomycosis, the case in Pilsen can be evaluated as uncommon. It was caused by Phialophora pedrosoi and passed as a skin form of chromomycosis. The lesion developed on the right forefinger of a patient who never visited tropical countries. She never was seriously ill, never treated with antibiotics, chemotherapeutics, or corticosteroids. The histological examination of the excision revealed a granuloma with histiocytes and many giant cells phagocytizing typical spherical brown microorganisms. The patient was cured by KI, intraiodine and X-ray therapy.
将着色芽生菌病的典型临床表现、真菌学和组织学基础与现今更常见的临床病程进行了比较。它还涉及血管、呼吸、淋巴系统、大脑的病变以及在免疫功能受损患者中的播散。因此,着色芽生菌病应归类为机会性真菌病。以皮肤结节为特征的暗色丝孢霉病非常罕见。皮下脓肿,也称为暗色真菌囊肿,更为常见,尤其是在使用皮质类固醇和免疫抑制治疗后。在三例捷克斯洛伐克着色芽生菌病病例中,比尔森的病例可被评估为不常见。它由裴氏瓶霉引起,表现为着色芽生菌病的皮肤型。病变发生在一名从未去过热带国家的患者的右手食指上。她从未患过重病,从未接受过抗生素、化疗药物或皮质类固醇治疗。切除组织的组织学检查显示有一个肉芽肿,其中有组织细胞和许多吞噬典型球形棕色微生物的巨细胞。该患者通过碘化钾、碘剂和X线治疗得以治愈。