Schmidt U, Metz K A, Schrader M, Leder L D
Institute of Pathology, University of Essen, Germany.
J Laryngol Otol. 1994 Mar;108(3):272-4. doi: 10.1017/s0022215100126519.
A 63-year-old woman presented with a history of increasing dysphagia of about two weeks duration. Laryngoscopy revealed a nonulcerated supraglottic epitheliomatous lesion that morphologically appeared well-differentiated and distinctly oncocytoid. Although the tumour lacked any criteria for malignancy such as cellular atypia, pleomorphism or necroses, it recurred twice after primary surgery and later gave rise to multiple painful skin metastases. The diagnosis of an oncocytoid differentiated neuroendocrine carcinoma of the larynx (laryngeal carcinoid) was made. Misinterpretation of laryngeal carcinoids is common, but can be avoided if one is familiar with this rare variant of laryngeal neoplasms.
一名63岁女性，有大约两周逐渐加重的吞咽困难病史。喉镜检查发现声门上区有一个非溃疡性上皮瘤样病变，形态学上显示为高分化且明显呈嗜酸性细胞样。尽管该肿瘤缺乏细胞异型性、多形性或坏死等任何恶性标准，但在初次手术后复发了两次，后来出现了多处疼痛性皮肤转移。最终诊断为嗜酸性细胞样分化型喉神经内分泌癌（喉类癌）。喉类癌的误诊很常见，但如果熟悉这种罕见的喉肿瘤变体，就可以避免误诊。
