Rojas-López M, Santos-Burgoa C, Ríos C, Hernández-Avila M, Romieu I
Instituto Nacional de Salud Pública, SSA, Cuernavaca, Mexico.
J Toxicol Environ Health. 1994 May;42(1):45-52. doi: 10.1080/15287399409531862.
Two isolated rural communities of Mexico were studied to assess the possible relationship between lead-glazed ceramics use and lead exposure. Women from these communities (n = 98) were asked to participate by filling out a general-purpose and exposure questionnaire in order to assess the individual contribution of ceramics to lead exposure. Blood samples were withdrawn to measure lead in blood and erythrocytic zinc protoporphyrin levels. Results were analyzed by multiple regression in order to find predictors of the dependent variables. Significant association between lead in blood and erythrocytic zinc protoporphyrin levels was identified with the following variables: storage in lead-glazed ceramics, cooking in lead-glazed ceramics, and meat and cheese consumption. The adjusted regression models explained 20-23% of the variance of the dependent variables (lead in blood and erythrocytic zinc protoporphyrin). A significant association (r2 = .38) was observed between lead in blood and lead in food prepared in lead-glazed ceramics in a subsample of 28 women. Results indicate that lead-glazed ceramics use may be the main predictor of lead in blood and erythrocytic zinc protoporphyrin levels in the rural communities studied.
对墨西哥两个偏远的农村社区进行了研究,以评估使用铅釉陶瓷与铅暴露之间可能存在的关系。来自这些社区的98名女性被要求填写一份通用的暴露情况调查问卷,以评估陶瓷对铅暴露的个体影响。采集血样以测量血液中的铅含量和红细胞锌原卟啉水平。通过多元回归分析结果,以找出因变量的预测因素。血液中的铅含量和红细胞锌原卟啉水平与以下变量之间存在显著关联:储存在铅釉陶瓷中、用铅釉陶瓷烹饪以及肉类和奶酪的摄入量。调整后的回归模型解释了因变量(血液中的铅和红细胞锌原卟啉)20%-23%的方差。在28名女性的子样本中,观察到血液中的铅与用铅釉陶瓷制备的食物中的铅之间存在显著关联(r2 = 0.38)。结果表明,在所研究的农村社区中,使用铅釉陶瓷可能是血液中铅含量和红细胞锌原卟啉水平的主要预测因素。