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无关供者骨髓移植中的口腔巨细胞病毒感染,可能由移植物抗宿主病及环孢素A的使用介导。

Oral cytomegalovirus infection in an unrelated bone marrow transplantation with possible mediation by graft-versus-host disease and the use of cyclosporin-A.

作者信息

LeVeque F G, Ratanatharathorn V, Dan M E, Orville B, Coleman D N, Turner S

机构信息

Harper Hospital, Detroit, MI 48201.

出版信息

Oral Surg Oral Med Oral Pathol. 1994 Mar;77(3):248-53. doi: 10.1016/0030-4220(94)90293-3.

DOI:10.1016/0030-4220(94)90293-3
PMID:8170655
Abstract

Graft-versus-host disease remains as a significant sequela in allogeneic bone marrow transplantation patients. Reports of oral presentations of cytomegalovirus infection in this patient population are rare. Although the usual manifestation of oral cytomegalovirus is mucosal ulceration, we report a case that we believe reflects a dynamic among graft-versus-host disease, cytomegalovirus, and the use of cyclosporin A, commonly used as an immunosuppressive agent in bone marrow transplantation.

摘要

移植物抗宿主病仍然是异基因骨髓移植患者的一个重要后遗症。关于该患者群体中巨细胞病毒感染的口腔表现的报道很少。虽然口腔巨细胞病毒的常见表现是黏膜溃疡,但我们报告了一例我们认为反映了移植物抗宿主病、巨细胞病毒以及在骨髓移植中常用作免疫抑制剂的环孢素A之间相互关系的病例。

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Oral cytomegalovirus infection in an unrelated bone marrow transplantation with possible mediation by graft-versus-host disease and the use of cyclosporin-A.无关供者骨髓移植中的口腔巨细胞病毒感染,可能由移植物抗宿主病及环孢素A的使用介导。
Oral Surg Oral Med Oral Pathol. 1994 Mar;77(3):248-53. doi: 10.1016/0030-4220(94)90293-3.
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[Gran versus host disease with oral involvement: report of one case].
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Oral complications and management strategies for patients undergoing cancer therapy.癌症治疗患者的口腔并发症及管理策略
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