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补骨脂素加紫外线A疗法治疗口腔慢性移植物抗宿主病:病例报告及文献综述

Treatment of oral chronic graft-versus-host disease with PUVA therapy: case report and literature review.

作者信息

Redding S W, Callander N S, Haveman C W, Leonard D L

机构信息

Department of General Dentistry, University of Texas Health Science Center, San Antonio, USA.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Aug;86(2):183-7. doi: 10.1016/s1079-2104(98)90123-8.

Abstract

Chronic graft-versus-host disease commonly appears with oral manifestations subsequent to allogeneic bone marrow transplantation. These manifestations include leukoplakia, mucosal atrophy, erythema, ulcers, and xerostomia. Some lesions are resistant to treatment with immunosuppressive medications. Ultraviolet A irradiation therapy with oral psoralen has been shown to be effective in treating these resistant lesions. This article presents a review of the literature and a case report.

摘要

慢性移植物抗宿主病通常在异基因骨髓移植后出现口腔表现。这些表现包括白斑、黏膜萎缩、红斑、溃疡和口干症。一些病变对免疫抑制药物治疗有抵抗性。口服补骨脂素的紫外线A照射疗法已被证明对治疗这些抵抗性病变有效。本文呈现了一篇文献综述和一个病例报告。

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