Schubert M M, Epstein J B, Lloid M E, Cooney E
Oral Medicine Service, Fred Hutchinson Cancer Research Center, Seattle, WA 98104.
J Oral Pathol Med. 1993 Jul;22(6):268-73. doi: 10.1111/j.1600-0714.1993.tb01069.x.
Herpes group virus infections in the immunocompromised host are associated with significant morbidity and mortality. Herpes simplex virus (HSV) and to a lesser extent varicella zoster virus (VZV) have long been recognized as causes of oral and peri-oral lesions in subjects undergoing bone marrow transplantation and in individuals infected with the Human Immunodeficiency Virus (HIV). A role for Cytomegalovirus (CMV) in such lesions is less clear and not well documented. This report describes two bone marrow transplant recipients and one individual infected with HIV in whom CMV was implicated as the cause of oral lesions. Diagnostic and management issues as well as clinical implications are discussed.
免疫功能低下宿主中的疱疹病毒组感染与显著的发病率和死亡率相关。单纯疱疹病毒（HSV）以及在较小程度上的水痘带状疱疹病毒（VZV）长期以来一直被认为是接受骨髓移植的受试者以及感染人类免疫缺陷病毒（HIV）的个体发生口腔和口周病变的原因。巨细胞病毒（CMV）在这类病变中的作用尚不清楚且记录不充分。本报告描述了两名骨髓移植受者和一名感染HIV的个体，其中CMV被认为是口腔病变的病因。文中还讨论了诊断和管理问题以及临床意义。
