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儿童假类风湿结节(深部环状肉芽肿):20例患者的临床病理特征

Pseudorheumatoid nodule (deep granuloma annulare) of childhood: clinicopathologic features of twenty patients.

作者信息

Evans M J, Blessing K, Gray E S

机构信息

Department of Pathology, Aberdeen University, United Kingdom.

出版信息

Pediatr Dermatol. 1994 Mar;11(1):6-9. doi: 10.1111/j.1525-1470.1994.tb00064.x.

Abstract

Pseudorheumatoid nodule of childhood is seen uncommonly by pathologists and is thought to be a variant of granuloma annulare. We report a series of 20 patients (13 M, 7 F) age 1 to 17 years. Fourteen lesions arose on the front of the lower limb, and 14 children had numerous lesions at diagnosis. Seven developed some form of recurrence, except for one case occurring at the site of the original lesion. Only one patient had a weakly positive rheumatoid factor, and was the patient with remote recurrence. As a significant number of lesions arose around the foot when the child was beginning to walk or starting to wear shoes, it is suggested that trauma plays a role in the development of some of these lesions.

摘要

儿童假性类风湿结节在病理学家中较少见,被认为是环状肉芽肿的一种变体。我们报告了一组20例患者(男13例,女7例),年龄在1至17岁之间。14个皮损出现在下肢前部,14名儿童在诊断时有多处皮损。7例出现了某种形式的复发,其中1例除外,其复发发生在原皮损部位。只有1例患者类风湿因子弱阳性,且是出现远期复发的患者。由于相当数量的皮损在儿童开始走路或开始穿鞋时出现在足部周围,提示创伤在其中一些皮损的发生中起作用。

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