Wautier J L, Tobelem G M, Peltier A P, Caen J P
Pathol Biol (Paris). 1975 Dec;23 suppl:33-6.
Studies of platelet C1 have been performed in 11 patients with chronic lymphocytic leukemia (CLL). The platelet C1 level evaluated by the hemolytic method was very low and the platelet aggregation induced by aggregated IgG or anti C1q antisera was significantly reduced. "In vitro", the lymphocytes from CLL were capable of inhibiting platelet C1 and platelet aggregation induced by aggregated IgG and anti C1q to a greater extent than normal lymphocytes. These results lead the authors to discuss the role of platelet C1 in the interaction platelet/immunoglobulins and the nature of the inhibition.
对11例慢性淋巴细胞白血病（CLL）患者的血小板C1进行了研究。通过溶血法评估的血小板C1水平非常低，且聚集的IgG或抗C1q抗血清诱导的血小板聚集显著降低。在“体外”，CLL患者的淋巴细胞比正常淋巴细胞更能抑制血小板C1以及聚集的IgG和抗C1q诱导的血小板聚集。这些结果促使作者讨论血小板C1在血小板/免疫球蛋白相互作用中的作用以及抑制的性质。
