Leaf D A
Department of Medicine, University of California Los Angeles.
Geriatrics. 1994 May;49(5):35-41.
The National Cholesterol Education Program Expert Panel has revised its recommendations for managing hypercholesterolemia in adults, including those at midlife and older. In utilizing these guidelines, it is important for the physician to develop an individualized approach to the older patient with hypercholesterolemia. Patient characteristics to consider include lifespan limitations, presence and severity of concomitant disease, mental status and cognitive ability, and the patient's expectations from medical care. Dietary intervention is the first step, with the major focus on restricting saturated fat and cholesterol. Lipid-lowering agents may be warranted in some patients to achieve target LDL levels. Minimize the risk of side effects by careful monitoring and using medications cautiously.
美国国家胆固醇教育计划专家小组已修订了其针对成人高胆固醇血症管理的建议，包括中年及老年人群。在运用这些指南时，医生为患有高胆固醇血症的老年患者制定个体化治疗方案非常重要。需要考虑的患者特征包括预期寿命限制、伴随疾病的存在及严重程度、精神状态和认知能力，以及患者对医疗护理的期望。饮食干预是第一步，主要重点是限制饱和脂肪和胆固醇的摄入。对于一些患者，可能需要使用降脂药物以达到低密度脂蛋白（LDL）目标水平。通过仔细监测和谨慎用药将副作用风险降至最低。
