Lugo G, Cipolla C, Bonfiglioli R, Sassi C, Maini S, Cancellieri M P, Raffi G B, Pisi E
Clinica Medica Generale e Terapia Medica, Università degli Studi di Bologna, Italy.
Int Arch Occup Environ Health. 1994;65(5):291-4. doi: 10.1007/BF00405691.
For some years, biological pest control has been re-evaluated as an alternative to the indiscriminate use of pesticides. The number of "bio-factories" in Europe has been constantly increasing and today more than 100 technicians work in mass rearing of arthropods. Seven cases of asthma and allergic rhinitis are reported in 13 workers engaged in the production of beneficial arthropods. The subjects suffered from attacks of asthma and rhinitis when they came into contact with eggs and scales or waste of Chrysoperla carnea, Leptinotarsa decemlineata, Ostrinia nubilalis and Ephestia kuehniella. These attacks occurred after an average exposure period of 18 months. A RAST test, prepared by Lofarma, was carried out on subjects' serum against the above-mentioned allergens and was positive in all symptomatic subjects (7 of 13) and negative in the others. This demonstrates IgE direct sensitization mediated by complete antigens.
多年来，生物害虫防治作为一种替代无差别使用杀虫剂的方法，一直在重新评估。欧洲“生物工厂”的数量一直在不断增加，如今有100多名技术人员从事节肢动物的大规模饲养工作。在13名从事有益节肢动物生产的工人中，报告了7例哮喘和过敏性鼻炎病例。这些受试者在接触粉蛉、马铃薯甲虫、欧洲玉米螟和地中海粉螟的卵、鳞片或粪便时，会出现哮喘和鼻炎发作。这些发作平均在接触18个月后出现。使用Lofarma公司制备的放射变应原吸附试验对受试者血清针对上述过敏原进行检测，所有有症状的受试者（13例中的7例）呈阳性，其他受试者呈阴性。这证明了由完全抗原介导的IgE直接致敏。
