Cipolla C, Lugo G, Sassi C, Bonfiglioli R, Maini S, Tommasini M G, Raffi G B
Instituto di Patologia Speciale Medica e Metodologia Clinica II e Medicina del Lavoro D. Campanacci, Università degli Studi di Bologna, Italy.
Int Arch Occup Environ Health. 1996;68(2):133-5. doi: 10.1007/BF00381246.
Allergic asthma and rhinoconjunctivitis have been reported in workers who are constantly in close contact with arthropods during the course of breeding and research. We investigated a group of ten people working with beneficial arthropods in a "bio-factory." The following tests were carried out: skin prick test with allergens present in the workplace, baseline pulmonary function test, aspecific bronchial provocation test with ultrasonically nebulized distilled water, and pulmonary function test after workplace exposure in two subjects. The results demonstrated a good correlation between skin prick test, previous RAST positive reactions, clinical symptoms, and exposure. Pulmonary function test after workplace exposure proved positive in one asthmatic subject and in one subject with rhinoconjunctivitis. It is concluded that the evidence supports the occupational nature of these allergic diseases and that there is a need for careful surveillance and environmental monitoring within the workplace.
在养殖和研究过程中经常与节肢动物密切接触的工人中,已报告出现过敏性哮喘和鼻结膜炎。我们对在一家“生物工厂”中与有益节肢动物打交道的一组十人进行了调查。进行了以下测试:用工作场所存在的过敏原进行皮肤点刺试验、基线肺功能测试、用超声雾化蒸馏水进行非特异性支气管激发试验,以及对两名受试者在工作场所接触后进行肺功能测试。结果表明,皮肤点刺试验、既往放射性变应原吸附试验阳性反应、临床症状和接触之间存在良好的相关性。在一名哮喘患者和一名鼻结膜炎患者中,工作场所接触后的肺功能测试结果呈阳性。结论是,证据支持这些过敏性疾病的职业性质,并且在工作场所需要进行仔细的监测和环境监测。