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摇蚊科双翅目昆虫的昆虫血红蛋白(Chi tI)是与环境、职业和爱好相关的重要过敏原。

Insect hemoglobins (Chi tI) of the diptera family Chironomidae are relevant environmental, occupational, and hobby-related allergens.

作者信息

Baur X, Liebers V

机构信息

Berufsgenossenschaftliches Forschungsinstitut für Arbeitsmedizin (BGFA), Institut an der Ruhr-Universität-Bochum, Federal Republic of Germany.

出版信息

Int Arch Occup Environ Health. 1992;64(3):185-8. doi: 10.1007/BF00380907.

DOI:10.1007/BF00380907
PMID:1399031
Abstract

Six hundred and forty-two persons with hobby-related (n = 205), occupational (n = 85), or environmental contact (n = 352) to the midge and larval allergen Chi tI were studied. Frequencies of IgE-mediated sensitization in these selected populations were 36.1%, 24.7%, and 9.6% respectively. Occupationally sensitized subjects who had been heavily exposed showed higher levels of antibodies, were more frequently diagnosed as having bronchial asthma and less frequently as having conjunctivitis, and had a significantly shorter latency period when compared to environmentally exposed people or aquarists. Our results are evidence for a higher risk of sensitization and of bronchial asthma in highly exposed subjects.

摘要

对642名与蠓及幼虫变应原Chit I有嗜好相关接触(n = 205)、职业接触(n = 85)或环境接触(n = 352)的人进行了研究。这些选定人群中IgE介导的致敏频率分别为36.1%、24.7%和9.6%。与环境接触者或水族饲养者相比,职业致敏且接触严重的受试者抗体水平更高,更常被诊断为患有支气管哮喘,较少被诊断为患有结膜炎,且潜伏期明显更短。我们的结果证明,高度接触者致敏和患支气管哮喘的风险更高。

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1
Insect hemoglobins (Chi tI) of the diptera family Chironomidae are relevant environmental, occupational, and hobby-related allergens.摇蚊科双翅目昆虫的昆虫血红蛋白(Chi tI)是与环境、职业和爱好相关的重要过敏原。
Int Arch Occup Environ Health. 1992;64(3):185-8. doi: 10.1007/BF00380907.
2
Chironomid midge allergy.摇蚊过敏
Arerugi. 1992 Feb;41(2 Pt 1):81-5.
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Evidence for haemoglobins as common allergenic determinants in IgE-mediated hypersensitivity to chironomids (non-biting midges).血红蛋白作为对摇蚊(非吸血蠓)IgE介导的超敏反应中常见变应原决定簇的证据。
Clin Allergy. 1985 Jul;15(4):335-43. doi: 10.1111/j.1365-2222.1985.tb03001.x.
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Humoral immune response to the insect allergen Chi t I in aquarists and fish-food factory workers.水族馆工作人员和鱼饲料厂工人对昆虫过敏原几丁质酶1的体液免疫反应。
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Patterns of immunoglobulin E sensitization to chironomids in exposed and unexposed subjects.暴露和未暴露人群对摇蚊的免疫球蛋白E致敏模式。
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本文引用的文献

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Humoral immune response to the insect allergen Chi t I in aquarists and fish-food factory workers.水族馆工作人员和鱼饲料厂工人对昆虫过敏原几丁质酶1的体液免疫反应。
Allergy. 1993 May;48(4):236-9. doi: 10.1111/j.1398-9995.1993.tb00722.x.
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The analysis of a protein-polymorphism. Evolution of monomeric and homodimeric haemoglobins (erythrocruorins) of Chironomus thummi thummi (Insecta, Diptera).
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Hypersensitivity to chironomids (non-biting midges): localization of the antigenic determinants within certain polypeptide sequences of hemoglobins (erythrocruorins) of Chironomus thummi thummi (Diptera).
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A new risk of occupational disease: allergic asthma and rhinoconjunctivitis in persons working with beneficial arthropods. Preliminary data.一种新的职业病风险:从事有益节肢动物工作的人员患过敏性哮喘和鼻结膜炎。初步数据。
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Evidence for haemoglobins as common allergenic determinants in IgE-mediated hypersensitivity to chironomids (non-biting midges).血红蛋白作为对摇蚊(非吸血蠓)IgE介导的超敏反应中常见变应原决定簇的证据。
Clin Allergy. 1985 Jul;15(4):335-43. doi: 10.1111/j.1365-2222.1985.tb03001.x.
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Immunological cross-reactivity of hemoglobins in the Diptera family Chironomidae.
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