Stein M, Spencer D, Kuten A, Bezwoda W
Department of Medical Oncology and Hematology, Johannesburg Hospital, Medical School and University of the Witwatersrand, South Africa.
Isr J Med Sci. 1994 Apr;30(4):298-305.
Infection with the human immunodeficiency virus (HIV) is the primary cause of AIDS and related disorders. Infection with HIV results in diminished cellular immunity, propensity to opportunistic infections, and an increased incidence of certain neoplasms. Kaposi's sarcoma (KS) is the most common neoplasm in persons infected with HIV. This epidemic, or HIV-related KS, usually follows an aggressive course with involvement of skin, lymph nodes, and internal organs. Normally, the disease has a progressive clinical course despite being responsive to radio- or chemotherapy.
人类免疫缺陷病毒(HIV)感染是艾滋病及相关疾病的主要病因。HIV感染会导致细胞免疫功能减退、易发生机会性感染以及某些肿瘤的发病率增加。卡波西肉瘤(KS)是HIV感染者中最常见的肿瘤。这种流行的、与HIV相关的KS通常进展迅速,会累及皮肤、淋巴结和内脏器官。通常情况下,尽管对放疗或化疗有反应,但该疾病仍有一个渐进性的临床病程。