• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

噪声暴露后猴子的听力损失与耳蜗病理变化

Hearing loss and cochlear pathology in monkeys after noise exposure.

作者信息

Hawkins J E, Johnsson L G, Stebbins W C, Moody D B, Coombs S L

出版信息

Acta Otolaryngol. 1976 Mar-Apr;81(3-4):337-43. doi: 10.3109/00016487609119971.

DOI:10.3109/00016487609119971
PMID:817561
Abstract

Old World monkeys were exposed to octaveband noise from 0.5 to 8 kHz at 120 dB SPL, 8 hours daily for 20 days. Restricted permanent threshold shifts and localized loss of outer hair cells were produced, which were reasonably well correlated with the exposure frequencies. There was also a loss of both inner and outer hair cells at the extreme basal end of Corti's organ, regardless of the exposure frequency. Implications for human inner ear pathology are discussed.

摘要

将旧大陆猴暴露于120分贝声压级、频率范围为0.5至8千赫的倍频带噪声中,每天8小时,持续20天。结果产生了永久性阈移受限和外毛细胞局部缺失,且这些结果与暴露频率具有较好的相关性。此外,无论暴露频率如何,柯蒂氏器最底部的内、外毛细胞均有缺失。文中还讨论了该研究对人类内耳病理学的意义。

相似文献

1
Hearing loss and cochlear pathology in monkeys after noise exposure.噪声暴露后猴子的听力损失与耳蜗病理变化
Acta Otolaryngol. 1976 Mar-Apr;81(3-4):337-43. doi: 10.3109/00016487609119971.
2
Hearing loss and cochlear pathology in the monkey (Macaca) following exposure to high levels of noise.
Arch Otorhinolaryngol. 1978 Mar 3;220(1-2):47-72. doi: 10.1007/BF00456301.
3
Effect of infrasound on cochlear damage from exposure to a 4 kHz octave band of noise.次声对暴露于4kHz倍频程噪声所致耳蜗损伤的影响。
Hear Res. 2007 Mar;225(1-2):128-38. doi: 10.1016/j.heares.2007.01.016. Epub 2007 Jan 19.
4
Noise-induced cochlear synaptopathy in rhesus monkeys (Macaca mulatta).恒河猴(猕猴)的噪声性耳蜗突触病变
Hear Res. 2017 Sep;353:213-223. doi: 10.1016/j.heares.2017.07.003. Epub 2017 Jul 8.
5
Effects of noise on inferior colliculus evoked potentials and cochlear anatomy in young and aged chinchillas.噪声对幼年和老年栗鼠下丘诱发电位及耳蜗解剖结构的影响。
Hear Res. 1998 Mar;117(1-2):81-96. doi: 10.1016/s0378-5955(98)00013-6.
6
Cochlear pathology in monkeys exposed to impulse noise.
Acta Otolaryngol Suppl. 1973;312:16-30. doi: 10.3109/00016487309125497.
7
Distribution of focal lesions in the chinchilla organ of Corti following exposure to a 4-kHz or a 0.5-kHz octave band of noise.暴露于4千赫或0.5千赫倍频程噪声后,豚鼠柯蒂氏器中局灶性病变的分布情况。
Hear Res. 2007 Mar;225(1-2):50-9. doi: 10.1016/j.heares.2006.12.012. Epub 2007 Jan 13.
8
The relationship between permanent threshold shift and the loss of hair cells in monkeys exposed to impulse noise.
Acta Otolaryngol Suppl. 1973;312:31-40. doi: 10.3109/00016487309125498.
9
Degeneration in the cochlea after noise damage: primary versus secondary events.噪声损伤后耳蜗的退变:原发性与继发性事件
Am J Otol. 2000 Jul;21(4):505-9.
10
Combined effects of noise and styrene exposure on hearing function in the rat.噪声与苯乙烯联合暴露对大鼠听力功能的影响
Hear Res. 2000 Jan;139(1-2):86-96. doi: 10.1016/s0378-5955(99)00174-4.

引用本文的文献

1
Recent Advances in Functionalized Nanoparticles for Targeted and Controlled Inner Ear Therapy via Localized Cochlear Delivery.通过局部耳蜗给药实现靶向和可控内耳治疗的功能化纳米颗粒的最新进展
J Audiol Otol. 2025 Jul;29(3):159-165. doi: 10.7874/jao.2025.00311. Epub 2025 Jul 18.
2
Oral Administration of TrkB Agonist, 7, 8-Dihydroxyflavone Regenerates Hair Cells and Restores Function after Gentamicin-Induced Vestibular Injury in Guinea Pig.口服TrkB激动剂7,8-二羟基黄酮可使豚鼠在庆大霉素诱导的前庭损伤后毛细胞再生并恢复功能。
Pharmaceutics. 2023 Feb 2;15(2):493. doi: 10.3390/pharmaceutics15020493.
3
Effect of N-acetyl-cysteine in prevention of noise-induced hearing loss: a systematic review and meta-analysis of randomized controlled trials.
N-乙酰半胱氨酸预防噪声性听力损失的效果:一项随机对照试验的系统评价和荟萃分析
Arch Med Sci. 2021 Mar 21;18(6):1535-1541. doi: 10.5114/aoms/109126. eCollection 2022.
4
WNT Activation and TGFβ-Smad Inhibition Potentiate Stemness of Mammalian Auditory Neuroprogenitors for High-Throughput Generation of Functional Auditory Neurons In Vitro.WNT 激活和 TGFβ-Smad 抑制增强了哺乳动物听觉神经祖细胞的干性,以便体外高通量生成功能性听觉神经元。
Cells. 2022 Aug 5;11(15):2431. doi: 10.3390/cells11152431.
5
Hearing Recovery Induced by DNA Demethylation in a Chemically Deafened Adult Mouse Model.化学性致聋成年小鼠模型中DNA去甲基化诱导的听力恢复
Front Cell Neurosci. 2022 Feb 17;16:792089. doi: 10.3389/fncel.2022.792089. eCollection 2022.
6
Dynamic patterns of YAP1 expression and cellular localization in the developing and injured utricle.YAP1 在发育和损伤耳石器中的表达和细胞定位的动态模式。
Sci Rep. 2021 Jan 25;11(1):2140. doi: 10.1038/s41598-020-77775-8.
7
Initiation of Supporting Cell Activation for Hair Cell Regeneration in the Avian Auditory Epithelium: An Explant Culture Model.鸟类听觉上皮中支持细胞激活以促进毛细胞再生的起始:一种外植体培养模型
Front Cell Neurosci. 2020 Nov 12;14:583994. doi: 10.3389/fncel.2020.583994. eCollection 2020.
8
Perspectives on Human Hearing Loss, Cochlear Regeneration, and the Potential for Hearing Restoration Therapies.关于人类听力损失、耳蜗再生及听力恢复疗法潜力的观点
Brain Sci. 2020 Oct 20;10(10):756. doi: 10.3390/brainsci10100756.
9
Changes in audiometric threshold and frequency selectivity correlate with cochlear histopathology in macaque monkeys with permanent noise-induced hearing loss.永久性噪声性听力损失猕猴的听阈和频率选择性变化与耳蜗组织病理学相关。
Hear Res. 2020 Dec;398:108082. doi: 10.1016/j.heares.2020.108082. Epub 2020 Sep 24.
10
The use of nonhuman primates in studies of noise injury and treatment.在噪声损伤和治疗研究中使用非人类灵长类动物。
J Acoust Soc Am. 2019 Nov;146(5):3770. doi: 10.1121/1.5132709.