Shai A, Avinoach I, Sagi A
Department of Plastic and Reconstructive Surgery, Soroka University Hospital, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
J Dermatol Surg Oncol. 1994 May;20(5):342-5. doi: 10.1111/j.1524-4725.1994.tb01635.x.
Spontaneous regression of malignant melanoma is characterized by a partial or complete disappearance of the neoplasm. Partial regression of melanoma has been documented in large series, but complete regression is reported as occurring only sporadically.
To describe a case of metastatic malignant melanoma where the primary lesion underwent spontaneous and complete regression and to review the literature pertaining to regression of melanoma.
The patient was examined clinically. Wide excision of the skin with the lesion was performed as well as left inguinal lymph node dissection.
Histologic examination of the lesion revealed complete regression of malignant melanoma. Examination of the lymph node dissected from the adjacent inguinal area revealed matastatic melanoma.
Greater attention should be devoted to identification of regression in melanoma, clinically and histologically, evaluating the prognostic implications which regression might indicate.
恶性黑色素瘤的自发消退表现为肿瘤部分或完全消失。黑色素瘤的部分消退在大量病例系列中已有记录，但完全消退仅偶尔有报道。
描述一例转移性恶性黑色素瘤，其原发灶出现自发完全消退，并回顾与黑色素瘤消退相关的文献。
对患者进行临床检查。对有病变的皮肤进行广泛切除，并进行左侧腹股沟淋巴结清扫。
病变的组织学检查显示恶性黑色素瘤完全消退。对从相邻腹股沟区域切除的淋巴结检查发现转移性黑色素瘤。
应更加关注在临床和组织学上识别黑色素瘤的消退情况，评估消退可能提示的预后意义。
