Jurgens T M, Frazier E G, Schaeffer J M, Jones T E, Zink D L, Borris R P, Nanakorn W, Beck H T, Balick M J
Merck Research Laboratories, Rahway, New Jersey 07065.
J Nat Prod. 1994 Feb;57(2):230-5. doi: 10.1021/np50104a006.
Curcuma comosa is a member of the economically important plant family, Zingiberaceae. A methanolic extract of C. comosa was shown to be nematocidal when tested against the free-living nematode Caenorhabditis elegans. Five diphenylheptanoids [1-5], one new and four known, have been isolated and shown to be responsible for the activity. This is the first report of three of these compounds [1, 2, 4] being isolated from a natural source.
