Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: the importance of a carbon-centered radical for antimalarial activity.
作者信息
Posner G H, Oh C H, Wang D, Gerena L, Milhous W K, Meshnick S R, Asawamahasadka W
机构信息
Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218.
出版信息
J Med Chem. 1994 Apr 29;37(9):1256-8. doi: 10.1021/jm00035a003.
PMID:8176702
Abstract
摘要
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