Besse P, Sicart M, Choussat A, Bricaud H
Arch Mal Coeur Vaiss. 1975 Dec;68(12):1277-88.
The authors report the haemodynamic changes observed during isometric stress corresponding to 30% of the maximum isometric effort, sustained for 3 minutes, in 22 normal subjects and 12 patients with cardiomyopathy. Echocardiographic study of the left ventricular diameters of 10 cardiac patients completes the work. The heart rate in normal subjects during effort increases by 45 +/- 30%, and the flow by 30 +/- 24%. The blood pressure is raised by +/- 25 +/- 8 mmHg, without significant change in the left ventricular end-diastolic pressure (less than +4 mmHg), or in peripheral resistance. The external work of the left ventricle increases by 75 +/- 41%, demonstrating an increase in the inotropic state of the myocardium. Max. vec. and the various indices of contractility are increased on average by +8.29 +/- 4.55 28 c/s. Adaptation to the increased pressure brings into play only the contractile reserve of the myocardium.
作者报告了22名正常受试者和12名心肌病患者在等长应激过程中观察到的血流动力学变化，等长应激相当于最大等长用力的30%，持续3分钟。对10名心脏病患者的左心室直径进行超声心动图研究完善了这项工作。正常受试者在用力时心率增加45±30%，血流量增加30±24%。血压升高±25±8 mmHg，左心室舒张末期压力（增加小于+4 mmHg）或外周阻力无明显变化。左心室的外部功增加75±41%，表明心肌收缩状态增加。最大向量和各种收缩性指标平均增加+8.29±4.55 28次/秒。对压力增加的适应仅动用了心肌的收缩储备。
