Moĭbenko A A, Grabovskiĭ L A, Zaĭchenko A P, Marchenko G I, Buriakov I E
Biull Eksp Biol Med. 1976;82(11):1291-4.
Changes in the cardiodynamics and the contractile myocardium function under experimental shock caused by intracoronary injection of the anticardial cytotoxic serum were studied on 20 anesthetized dogs. Along with the symptoms of disturbance of the left ventricle function (a decrease of the systolic index, stroke work index of the left ventricle, rate of the intraventricular pressure rise, indices of myocardial contractility, ejection fraction) a decrease of the end-diastolic volume and pressure in the left ventricle was observed. These data show that disturbances in the cardiodynamics were cause not only by the cytotoxic heart damage, but also by derangement of the blood flow to the left heart.
在20只麻醉犬身上研究了冠状动脉内注射抗心肌细胞毒性血清所致实验性休克时心脏动力学和收缩性心肌功能的变化。除了左心室功能紊乱的症状(左心室收缩指数、每搏功指数、心室内压上升速率、心肌收缩性指数、射血分数降低)外,还观察到左心室舒张末期容积和压力降低。这些数据表明,心脏动力学紊乱不仅是由细胞毒性心脏损伤引起的,也是由左心血流紊乱引起的。