Darendeliler E, Ayan I, Kebudi R, Ağaoğlu L, Bilge N, Kinay M
Department of Radiation Oncology, University of Istanbul, Topkapi, Turkey.
Med Pediatr Oncol. 1994;23(1):60-3. doi: 10.1002/mpo.2950230111.
Spinal canal involvement is not a common pattern of metastasis in Wilms' tumor. Although early detection and treatment can achieve improvement of neurological deficit, mortality remains high. We present a 5-year-old girl who had an epidural metastasis while she was receiving chemotherapy for stage IV Wilms' tumor. Within 2 months following laminectomy, total removal of tumor, radiotherapy, and adjuvant chemotherapy some of the neurological signs improved.
椎管受累在肾母细胞瘤转移中并非常见模式。尽管早期发现和治疗可使神经功能缺损得到改善,但死亡率仍然很高。我们报告一名5岁女孩,她在接受IV期肾母细胞瘤化疗时发生了硬膜外转移。在椎板切除、肿瘤全切、放疗及辅助化疗后的2个月内,部分神经体征有所改善。