von Wietersheim J, Köhler T, Feiereis H
Clinic for Psychosomatics and Psychotherapy, Medical University of Lübeck, FRG.
Psychother Psychosom. 1992;58(2):103-12. doi: 10.1159/000288617.
This study examined whether life event stress under general or more specific conditions (fear of separation, feeling of being under pressure, feeling of being caught between two quarreling parties, separation experiences) contribute to the aggravation of inflammatory bowel disease (IBD). Firstly, 51 patients with ulcerative colitis, 57 patients with Crohn's disease, and 60 controls were compared in terms of these variables. In addition, the IBD patients filled out questionnaires asking for life events, the specific psychological conditions mentioned above, and their symptoms every 3 months for 1 year after the first measurement. Patients with Crohn's disease and patients with ulcerative colitis reported a lower amount of life event stress than members of the control group, but listed more feelings of being under pressure. Within group comparisons between patients in relapse and patients in remission, as well as comparisons between patients with recently increased disease activity and patients without increased disease activity did not yield clear results. We conclude that the variables in question have little influence on the beginning of a relapse.
本研究调查了一般或更特定条件下的生活事件压力（对分离的恐惧、压力感、夹在两个争吵方之间的感觉、分离经历）是否会导致炎症性肠病（IBD）加重。首先，对51例溃疡性结肠炎患者、57例克罗恩病患者和60名对照者在这些变量方面进行了比较。此外，IBD患者在首次测量后的1年里，每3个月填写一次问卷，询问生活事件、上述特定心理状况以及他们的症状。克罗恩病患者和溃疡性结肠炎患者报告的生活事件压力量低于对照组，但列出的压力感更多。在复发患者与缓解期患者之间的组内比较，以及疾病活动近期增加的患者与疾病活动未增加的患者之间的比较，均未得出明确结果。我们得出结论，所讨论的变量对复发的开始影响很小。
