Heys S D, O'Hanrahan T J, Brittenden J, Eremin O
Department of Surgery, University of Aberdeen, UK.
Eur J Surg Oncol. 1994 Jun;20(3):225-31.
Colorectal cancer in patients under 45 years of age accounts for approximately 4% of all cases of colorectal cancer. The stage of disease at presentation is comparable with that of older patients. Histological evaluations of the cancers in the younger age group of patients reveal that approximately four times as many tumours are of the mucinous type and this is associated with an increased risk of local recurrence. Dukes staging and vascular invasion by tumour are prognostic indicators for overall patient survival. However, survival rates for young patients with colorectal cancer are comparable to those of older patients, when considering equivalent Dukes stages.
45岁以下患者的结直肠癌约占所有结直肠癌病例的4%。就诊时疾病分期与老年患者相当。对年轻患者组癌症的组织学评估显示，黏液型肿瘤的数量约为其他类型的四倍，且这与局部复发风险增加相关。Dukes分期和肿瘤血管侵犯是患者总体生存的预后指标。然而，考虑到Dukes分期相当，年轻结直肠癌患者的生存率与老年患者相当。
